Limitless Exam: 14.1.3 Synapse
Chemical Transmission Across the Gap
Bio-Realism V2: Synapse Structure
📋 Section A: Paper 2 - Multiple Choice (5 Questions)
1 mark per question • Definition & Basic Concepts
What is a synapse?
How does the signal travel across the synaptic gap?
Where are neurotransmitters stored before release?
What happens when a neurotransmitter binds to a receptor?
Which structure contains receptors for neurotransmitters?
✍️ Section B: Paper 4 - Structured Theory (5 Questions)
Variable marks • Keyword Detection • Model Answers
Study the diagram of a synapse above. Label the following structures: A (Synaptic vesicle), B (Synaptic cleft), C (Receptor protein).
[3 marks]Describe how an impulse is transmitted across a synapse. [6 marks]
[6 marks]Explain why there is a delay when signals cross a synapse. [2 marks]
[2 marks]State what happens to neurotransmitter molecules after they have transmitted the signal. [2 marks]
[2 marks]Suggest why some drugs affect synaptic transmission. [3 marks]
[3 marks]🔬 Section C: Paper 6/4 - Application & Experimental (5 Questions)
Variable marks • One-Way Transmission • Experimental Design
Explain how synapses ensure one-way transmission of nerve impulses. [4 marks]
[4 marks]A student investigates reaction time using a ruler drop test. The ruler is dropped and caught. Suggest why there is always a minimum reaction time, even for the fastest person. [3 marks]
[3 marks]Describe how you would use the ruler drop test to investigate the effect of caffeine on reaction time. Include variables and safety. [5 marks]
[5 marks]A neurotoxin prevents vesicles from releasing neurotransmitters. Predict the effect on nerve transmission. [2 marks]
[2 marks]Explain why synapses allow more complex responses than a simple reflex arc. [3 marks]
[3 marks]Cambridge IGCSE Biology 0610 (2026-2028 Syllabus)
Topic 14.1.3: Synapse • Chemical Transmission Mechanism
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